This is kind of a contrast from the other thread. But just make sure not to make them that obvious (for instance you can't have Bob Saget playing the role of a baby girl or something

). It is a harder thread to do, but I'll try...
Bob Saget -
a baby girl - oops almost forgot my own rule

- a sensitive WWI veteran
Dave Coulier - intimidating boxer
John Stamos - eclectic marathon runner
Candace Cameron - hardcore atheist
Jodie Sweetin - a royal queen
MK&A Olsen - wise buddy who doesn't care what other people think
Lori Loughlin - serial killer
Andrea Barber - the lead cheerleader